Our primary research area focuses on how airway mucus supports anaerobic bacterial growth and metabolism, revealing how mucin degradation and cross-feeding by commensals influence pathogen behavior.

We also explore the microbial ecology of chronic sinusitis, examining how anaerobic and opportunistic bacteria interact to shape inflammation, biofilm formation, and persistent infection in the upper airways.

We investigate the link between CFTR dysfunction, gut microbial dysbiosis, and the increased incidence of colorectal cancer in the aging CF population. We specifically focus on interactions between CF-associated bacteria like Fusobacterium nucleatum, microbial metabolites, and tumorigenic pathways.